Hello,
Upgrading from 4.1.0022 to the latest version 4.3.0181 will not provide any benefits or new features for your RSA306B. Version 4.3.0181 simply adds new capabilities and features for our oscilloscopes. It should still function the same as 4.1.0022 as far as I know if you accidently installed the later version. It just hasn't been officially tested with the USB powered RSAs, therefore it cannot be recommended.